GI Problem

& solution

How does Livaux® work?

Professor Richard Gearry on F. prau

Why is there so much interest in the scientific community for F. prau?

As science has been able to delve into the microbiome that inhabits our gut with new advances, it has become clear that some microbes are present more often in health than others, while some microbes are more commonly found in disease. F. prau has consistently been found to be present in higher concentrations in health.

What diseases are associated with low levels of F. prau?

Low levels of F. prau have been found in people with inflammatory bowel disease (Crohn’s disease and ulcerative colitis), asthma, obesity and even depression. However, it is not clear whether these associations are cause or effect.

Can you take a probiotic supplement containing F. prau?

F. prau is an obligate anaerobe, therefore a probiotic preparation is unlikely to be effective as the preparation may not allow the bacterium to survive. Increasing the concentration of F. prau using a prebiotic just makes more scientific sense.

How can you boost your natural levels of F. prau then, if you can’t supplement with a probiotic?

In theory, increasing F. prau could be achieved using a probiotic supplement including F. prau although it can be technically difficult to achieve this. An alternative that is more likely to succeed is to provide the microbiome with foods that favour the growth of F. prau.

What are the potential beneficial effects of boosting your F. prau levels in the gut?

Higher levels of F. prau are found in healthy individuals when compared to people with a range of illnesses. While this does not mean that F. prau protects people from these illnesses, it would seem that achieving higher levels of F. prau in the microbiome is not a bad aim.

Why is there so much interest in the scientific community for F. prau?

As science has been able to delve into the microbiome that inhabits our gut with new advances, it has become clear that some microbes are present more often in health than others, while some microbes are more commonly found in disease. F. prau has consistently been found to be present in higher concentrations in health.

What diseases are associated with low levels of F. prau?

Low levels of F. prau have been found in people with inflammatory bowel disease (Crohn’s disease and ulcerative colitis), asthma, obesity and even depression. However, it is not clear whether these associations are cause or effect.

Can you take a probiotic supplement containing F. prau?

F. prau is an obligate anaerobe, therefore a probiotic preparation is unlikely to be effective as the preparation may not allow the bacterium to survive. Increasing the concentration of F. prau using a prebiotic just makes more scientific sense.

How can you boost your natural levels of F. prau then, if you can’t supplement with a probiotic?

In theory, increasing F. prau could be achieved using a probiotic supplement including F. prau although it can be technically difficult to achieve this. An alternative that is more likely to succeed is to provide the microbiome with foods that favour the growth of F. prau.

What are the potential beneficial effects of boosting your F. prau levels in the gut?

Higher levels of F. prau are found in healthy individuals when compared to people with a range of illnesses. While this does not mean that F. prau protects people from these illnesses, it would seem that achieving higher levels of F. prau in the microbiome is not a bad aim.

F. prau is a hero within your gut microbiome

There are heroes within your gut microbiome, including lactobacilli and bifidobacteria. Only recently, an intestinal bacterium called Faecalibacterium prausnitzii (F. prau) was found to be very important for gut flora balance.

F. prau is one of the most abundant bacteria in the human gut ecosystem. Low numbers have been associated with irritable bowel syndrome (IBS), inflammatory bowel diseases (IBD, including ulcerative colitis and Crohn’s disease) and coeliac disease3.

3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667473/

How to improve gut microbiome

After learning about the importance of F. prau in your gut microbiome, you might think “I need to swallow some F. prau to increase my internal population”, or something along these lines.

However increasing diminished F. prau populations isn’t that easy. Oxygen kills F. prau, so it can’t easily be packaged up as a probiotic supplement. The only effective strategy for improving F. prau levels is to help your existing F. prau population to thrive.

That’s where Livaux® can help. Derived from non-GMO New Zealand Zespri® SunGold kiwifruit grown in New Zealand, Livaux® is a freeze-dried powder concentrate that can be ingested to help native F. prau communities to flourish. It has a patent pending.

An Anagenix clinical study showed that F. prau levels increased doubled after Livaux® treatment, going from 3.4% to 7.0%. Study participants also noted an improvement in their ‘general feeling of wellness’ following a course of Livaux®.4

4. Consumption of kiwifruit capsules increase Faecalibacterium prausnitzii abundance in functionally constipated individuals: a randomised controlled human trial Paul Blatchford , Halina Stoklosinski, Sarah Eady, Alison Wallace, Christine Butts,Richard Gearry, Glenn Gibson , Juliet Ansell. Publication pending.